Applied physics and mathematics in medicine and pharmacy
1. General Information
- form of study: full-time / combined
- number of accepted students to the form: 1 / 1
- language of study: Czech / English
- standard length of study: 4 years
- form of entrance examination: oral
- validity of accreditation: until 29th May 2034
- education field: General Medicine and Dentistry (55 %), Pharmacy (45 %)
- providing faculty: FoM HK CU, FoP CU
- study program guarantor: prof. Ing. Jan Kremláček, Ph.D., doc. Dipl.-Math. Erik Jurjen Duintjer Tebbens, Ph.D.
Study Program Characteristics
The doctoral programme Applied Physics and Mathematics in Medicine and Pharmacy is primarily intended for graduates of master's degree programmes oriented towards biomedicine, natural, exact, and technical sciences. The aim of the doctoral programme is the postgraduate education, training, and scientific development of professionals in the areas of materials research, biophysical interactions, imaging methods, biostatistics, and of mathematical and computer modeling in medicine and pharmacy.
Information on Graduate Employment
The graduate of the interdisciplinary doctoral programme Applied Physics and Mathematics in Medicine and Pharmacy is versatile and prepared to work in an academic-scientific research workplace (e.g. in biophysical and pharmaceutical laboratories, in interdisciplinary teams in clinics or workplaces developing medical products, aids, devices of software) with a biomedical focus. The graduate has a detailed overview of medical biophysics and or mathematical biology in pharmacy and related medical, scientific, and technical fields. She/he can apply and extend biophysical or biostatistical research methods in scientific work at all levels, from basic to applied research. She/he can independently and critically evaluate new knowledge in accordance with the principles of evidence-based medicine and pharmacy, design a scientific experiment to address scientific questions of a biophysical, mathematical, or bio-informatic nature, prepare a grant application for research support, and interpret, discuss, and present the results of scientific work.
2. Entrance Examination
Framework Content of the Entrance Examination
Oral exam in fields of Physics, Mathematics applied in Medicine and Pharmacy focusing on the previous study, theses, and expectations for the future doctoral study.
Presentation of the proposed doctoral project.
Part of the exam is conducted in the English language to assess the knowledge (at least C1 level is required).
Conditions of Admission
A necessary but not sufficient requirement for acceptance to the doctoral study program is a completed master's degree.
Additional Conditions for Bonus Points (e.g. Practice)
Completed master's degree program focused on medicine, pharmacy, bioinformatics, bioengineering or a natural science field related to doctoral program in Applied physics and mathematics in medicine and pharmacy (rated 2 points). Practice in a fields related to the doctoral program of Applied physics and mathematics in medicine and pharmacy (rated 3 points). Indication of the supposed training center and the approval of a specific supervisor with the management of the planned doctoral project (rated max. 5 points).
Criteria for the Evaluation Exams
- Level of expertise – assessment based on answers to the questions from the range of topics listed in the Framework content of the entrance exam (max. 10 points).
- Submitted doctoral research project – the project's complexity, modern methodological approaches for solutions and the continuity of the project with topics already addressed in the doctoral program and the financial coverage of the project are evaluated (max. 10 points).
The minimum admission limit is 20 points out of 30.
The Dean decides to accept the applicant(s) who have fulfilled the conditions of the admission procedure and, according to the number of points achieved, ranked in the order corresponding to the predetermined number of accepted applicants for the particular program.
Dates
- deadlines and detailed information about the admission procedure
- currently announced dissertation themes
3. Framework Study Plan
Study obligations
The student is required to complete at least two mandatory elective DSP subjects from the list below. The supervisor will recommend the choice of subjects that are approved by the Subject Co-ordinating Board of Ph.D. programme as part of the individual study plan.
- Introduction to Research Work
- Medical Biophysics and Biostatistics
- Atomistic Simulation
- Biophysics of Lipids
- Radioactively Labeled Biologically Active Substances
- Computer-aided Drug Design
- Introduction to Mathematical Biology
- English Language
- Basic statistics for doctoral study
The student actively participates in professional events in the Czech Republic and abroad, presenting independently achieved results. He publishes in foreign professional periodicals with an impact. The obligations and content of doctoral studies are determined for each student in an individual study plan (ISP), including a timetable, fulfillment of which is subject to regular annual evaluation by the Subject Co-ordinating Board of Ph.D. programme.
Publication activity requirements
The minimum requirement for the publication of a doctoral program student's creative output for starting the procedure for the defense of a dissertation is set as follows:
- the student must be the author of at least two original scientific papers thematically related to the topic of the dissertation thesis accepted for publication. These publications must be in journals with a current IF higher than 0.5 (assessed as of the month the paper was accepted) and the student must be the first author of at least one of them.
or
- the student must be the first author of an original scientific work thematically related to the topic of the dissertation thesis accepted for publication in a journal with IF which is ranked in Q1 according to the current AIS (assessed as of the month the work was accepted). In case a given journal is listed in more than one category according to WoS, Q1 according to AIS for the field of the dissertation will be considered.
The number of mandatory publications cannot include publications of the type "letter to the editor", discussion of other scientific work, "short communication", editorial, etc. The quality and admissibility (acceptability) of a publication that does not meet the type of original scientific works mentioned above under a) or b), but will be a very significant publication: a patent, a new methodology, a high-quality overview publication, etc., will be assessed by the Subject Area Board and the Vice-Dean for doctoral study programs at the faculty where the student is enrolled.
Requirements for completing internships
During the course of the studies, the student completes an internship at a foreign workplace for a total of at least three months, when it is possible to divide this time into a maximum of three parts. During the internship, the student tackles a part of his research project and consults, develops and analyzes the research results and related topics related to the dissertation.
Other study obligations
Evaluation of the course of study is carried out in a standard process within the framework of four milestones ( continuous study evaluations with a check on the fulfillment of study obligations), which is evaluated by the Subject Area Board independently of the supervisor:
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after 6 months from the beginning of the study - the student presents at least a 5-page (A4) description of the research project on the topic of the dissertation thesis with a clear declaration of the current state of the issue, hypotheses, scientific questions, main and secondary goals of the research project (work), methods applied, expected scientific contribution and financial balance. An overview of literary sources is not included in the scope of the above description. This requirement can be met by submitting a GAUK grant or an equivalent scientific project in the 1st section of the study;
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by the end of the first study year at the latest, the student presents the results achieved and mastered methods in the form of an entry in the SIS;
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by the end of the second study year at the latest, the student presents research data processed using statistical methods and a copy of the written application for grant support for the solution of the research project or documents active involvement in the supervisor's grant project and submits it into the SIS;
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by the end of the fourth study year at the latest, the student presents the first-author manuscript of the original scientific work, which, according to the supervisor, is prepared to be sent to a journal with an IF ≥ 0.5 and inserted into the SIS, and at the same time documents an overview of the presentations of the results of the research project at professional scientific events.
The following obligations of the student and their entry into SIS result from the above:
- submission of student's own research project on the topic of the dissertation,
- submission of a separate application proposal for grant support or active involvement in the supervisor´s grant,
- presentation of the results of student's own scientific work at a professional event/conference as the presenting author,
- preparation of the first-author manuscript of the original scientific work, which is the subject of the dissertation, for a journal with an IF higher than 0.5.
Dissertation themes
State Doctoral Examination
The state doctoral examination focuses on the scientific basis of the field and disciplines related to the topic of the dissertation. The state doctoral examination will be conducted in the form of an interview with a focus on the doctoral student's broader research areas together with the defense of the dissertation.
4. Human Resources
Subject Area Board
Subject Area Board Chair and study program guarantor
- prof. Ing. Jan Kremláček, Ph.D.,
Vice-Chair and guarantor of the study program for Faculty of Pharmacy CU
- doc. Dipl.-Math. Erik Jurjen Duintjer Tebbens, Ph.D.
Members of Subject Area Board
- doc. RNDr. Aleš Bezrouk, Ph.D.
- doc. Dipl.-Math. Erik Jurjen Duintjer Tebbens, Ph.D.
- doc. Ing. Josef Hanuš, CSc.
- doc. RNDr. Iveta Hnětynková, Ph.D.
- prof. RNDr.Hana Kolářová, CSc.
- prof. Ing. Jan Kremláček, Ph.D.
- doc. Ing. Petra Matoušková, Ph.D.
- Mgr. Petra Pullmanová, Ph.D.
- doc. RNDr. Karel Volenec, CSc.
Other members of the State Doctoral Examination and Dissertation Defense Committees other than the members of the Subject Are Board
- Mgr. Pavel Bárta, Ph.D.
- Mgr. Veronika Bernhauerová, Ph.D.
- Eugen Hruška, Ph.D.
- prof. MUDr. RNDr. Milan Kaška, Ph.D.
- Mgr. Zuzana Novická
- Mgr. Jana Pavlíková Přecechtělová, Ph.D.
- doc. PharmDr. Jan Zitko, Ph.D.
5. Research Groups
Research groups lead by supervisors of doctoral study program Bioanalytical Methods
In silico models, statistics and other mathematical approaches used in pharmaceutical and biomedical sciences
Matematical pharmacy
Leader: doc. Dipl.-Math. Erik Jurjen Duintjer Tebbens, Ph.D.
Research Group of Xenobiotic Resistance Mechanisms
Leader: doc. Ing. Petra Matoušková, Ph.D.